Annexin A
AnxA
Annexin A Isoform Specific Products
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Annexin A
(18)
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AnxA1
(5)
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AnxA2
(1)
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AnxA3
(2)
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AnxA4
(1)
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AnxA6
(1)
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AnxA7
(1)
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AnxA8
(1)
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AnxA9
(1)
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AnxA10
(1)
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AnxA11
(1)
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AnxA13
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All Product Categories
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Annexin A Related Products (34)
Related Products (34)
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Annexin A Isoform Comparison
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CI-936
0 ImagesCat. No.: HY-106752CAS No.: 98383-40-5Synonyms: MRS-3310CI-936 (MRS-3310) is an orally active A2 agonist with 25 nM affinity. CI-936 produces potent and selective effects in preclinical tests predictive of antipsychotic efficacy. CI-936 inhibits exploratory activity in mice.
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PY-PAP
0 ImagesCat. No.: HY-176548CAS No.: 2765218-57-1PY-PAP is a photoactivatable affinity probe and a derivative of PY-60 (HY-141644). PY-PAP retains the cellular function of activating YAP transcriptional activity. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through ultraviolet crosslinking and click reactions. PY-PAP plays a key role in identifying ANXA2 as the specific target of PY-60.
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A11 acetate
0 ImagesCat. No.: HY-P10412APurity: 98.48%Synonyms: ANXA1-derived 11 amino acid-long peptide acetateA11 (ANXA1-derived 11 amino acid-long peptide) acetate is a ANXA1-EphA2 interaction-blocking peptide. A11 acetate reduces ANXA1 bound to EphA2 and increases Cbl (the E3 ubiquitin ligase of EphA2) bound to EphA2. A11 acetate inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells. A11 acetate inhibits angiogenesis. A11 acetate can be used in studies related to nasopharyngeal carcinoma.
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ANXA3 degrader 1
0 ImagesCat. No.: HY-168950ANXA3 degrader 1 is a degrader targeting annexin A3 (ANXA3), with DC50 values of 1.32 μM and 3.12 μM in MDA-MB-231 and MDA-MB-468 cells, respectively, and exhibits selective activity against ANXA3 relative to other members of the annexin family. ANXA3 degrader 1 induces selective degradation of ANXA3 via the ubiquitin-proteasome pathway rather than autophagy. ANXA3 degrader 1 can be used for research on triple-negative breast cancer.
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Linsidomine hydrochloride (Standard)
0 ImagesSynonyms: SIN-1 chloride (Standard)Linsidomine (hydrochloride) (Standard) is the analytical standard of Linsidomine (hydrochloride). This product is intended for research and analytical applications. Linsidomine hydrochloride (SIN-1 chloride) is a spontaneous ROS/RNS generator and peroxynitrite donor. Linsidomine hydrochloride is a vasodilator and platelet aggregation inhibitor. Linsidomine hydrochloride induces oxidative stress-induced chondrocyte apoptosis and necrosis. Linsidomine hydrochloride inhibits the migration, proliferation and neointima formation of vascular smooth muscle cells by inhibiting the expression of annexin A2. In addition, low doses of Linsidomine hydrochloride shows protective effects on Zn2+ treated nerve cells.
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Hydrocortamate hydrochloride
0 ImagesHydrocortamate hydrochloride is a broad-spectrum immunosuppressant. Hydrocortamate hydrochloride has been identified as a potential inhibitor of T cell proliferation in ischemia-reperfusion injury (IRI), specifically targeting the ANXA1 gene. Hydrocortamate hydrochloride can be used in inflammation research.
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Anxa4 Rat Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS25291Anxa4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Anxa4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Anxa4 siRNA-1: 5 nmol (HPLC)
Anxa4 siRNA-2: 5 nmol (HPLC)
Anxa4 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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Anxa13 Rat Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS24560Anxa13 Rat Pre-designed siRNA Set A contains three designed siRNAs for Anxa13 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Anxa13 siRNA-1: 5 nmol (HPLC)
Anxa13 siRNA-2: 5 nmol (HPLC)
Anxa13 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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PF-04217903 phosphate
0 ImagesCat. No.: HY-12017CCAS No.: 1159490-83-1PF-04217903 phosphate is an orally active, highly selective ATP-competitive c-Met kinase inhibitor with a Ki value of 4.8 nM and a Kd value of 4.5 nM. PF-04217903 phosphate blocks c-Met and HGF signaling pathways, inhibits MET phosphorylation, and blocks downstream MAPK, PI3K/AKT and PLCγ1 pathways. PF-04217903 phosphate suppresses tumor proliferation, survival, migration, invasion, angiogenesis and metastasis, induces apoptosis, and enhances efferocytosis, Annexin A1 expression and resolution of inflammation. PF-04217903 phosphate retains activity against several c-Met mutants (M1131T, V1220I, H1094R). PF-04217903 phosphate increases the incidence of subarachnoid hemorrhage and reduces survival rate without altering aneurysm formation, and also prevents lymph node metastasis induced by VEGF inhibition. PF-04217903 phosphate is applicable to research related to tumors (pancreas, stomach, lung, brain, colon, breast, kidney, melanoma, etc.), intracranial aneurysms and inflammatory diseases (gouty arthritis, neutrophilic pleuritis).
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Anxa10 Mouse Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS17563Anxa10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Anxa10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Anxa10 siRNA-1: 5 nmol (HPLC)
Anxa10 siRNA-2: 5 nmol (HPLC)
Anxa10 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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Anxa6 Rat Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS24635Anxa6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Anxa6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Anxa6 siRNA-1: 5 nmol (HPLC)
Anxa6 siRNA-2: 5 nmol (HPLC)
Anxa6 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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PY-60 (Standard)
0 ImagesCat. No.: HY-141644RCAS No.: 2765218-56-0PY-60 (Standard) is the analytical standard of PY-60 (HY-141644). This product is intended for research and analytical applications. PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 µM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity.
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Anxa9 Rat Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS27368Anxa9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Anxa9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Anxa9 siRNA-1: 5 nmol (HPLC)
Anxa9 siRNA-2: 5 nmol (HPLC)
Anxa9 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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Anxa8 Rat Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS25659Anxa8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Anxa8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
Anxa8 siRNA-1: 5 nmol (HPLC)
Anxa8 siRNA-2: 5 nmol (HPLC)
Anxa8 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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