Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11098)
Related Products (11098)
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Cycloguanil-d6 nitrate
0 ImagesCat. No.: HY-12784S1CAS No.: 2070015-19-7Synonyms: Chlorguanide triazine-d6 nitrateCycloguanil-d6 (Chlorguanide triazine-d6) nitrate is the deuterium labeled Cycloguanil nitrate. Cycloguanil nitrate is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil nitrate blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil nitrate inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil nitrate also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity.
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13-cis Acitretin-d3
0 ImagesCat. No.: HY-129240SCAS No.: 1185241-03-5Synonyms: Isoacitretin d3; Ro 13-7652 d313-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
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D(-)-Fructose-18O-1
0 ImagesCat. No.: HY-N7092S20Synonyms: D-Fructose-18O-1D(-)-Fructose-18O-1 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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Propantheline-d3 iodide
0 ImagesCat. No.: HY-142328SPropantheline-d3 (iodide) is the deuterium labeled Propantheline iodide.
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Desamino P-ethoxy glufosinate ethyl ester-d3
0 ImagesCat. No.: HY-W702984CAS No.: 1346598-74-0Desamino P-ethoxy glufosinate ethyl ester-d3 is the deuterium labeled Desamino P-ethoxy glufosinate ethyl ester.
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Tauro-obeticholic acid-d5 sodium
0 ImagesCat. No.: HY-135399STauro-obeticholic acid-d5 sodium is deuterium labeled Tauro-obeticholic acid sodium (HY-135399A). Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist.
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Azelastine-13C,d3 hydrochloride
0 ImagesCat. No.: HY-B0462SAzelastine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Azelastine hydrochloride. Azelastine-13C,d3 (hydrochloride), an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine-13C,d3 (hydrochloride) can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2.
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DL-Mevalonolactone-d4
0 ImagesCat. No.: HY-W752587CAS No.: 349553-98-6Synonyms: (±)-Mevalonolactone-d4; Mevalolactone-d4DL-Mevalonolactone-d4 ( (±)-Mevalonolactone-d4) is the deuterium labeled DL-Mevalonolactone (HY-107855). DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy. DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling.
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1,2-Distearoyl-sn-glycero-3-phosphate-d70 sodium
0 Images1,2-Distearoyl-sn-glycero-3-phosphate-d70 (sodium) is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphate.
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2′-Deoxyguanosine 5′-monophosphate-15N5,d12 dilithium
0 ImagesCat. No.: HY-W393970SSynonyms: 5'-Deoxyguanylic acid-15N5,d12 dilithium2′-Deoxyguanosine 5′-monophosphate-15N5,d12 (5'-Deoxyguanylic acid-15N5,d12) dilithium is deuterium and 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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N-Desmethyl venlafaxine-d3
0 ImagesCat. No.: HY-W295339SCAS No.: 1189980-40-2N-Desmethyl venlafaxine-d3 is a deuterium labeled compound.
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4-hydroxy Nonenal Glutathione-d3 TFA
0 ImagesCat. No.: HY-139965S4-hydroxy Nonenal Glutathione-d3 (TFA) is the deuterium labeled 4-hydroxy Nonenal Glutathione (TFA).
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4-Hydroxyphenylacetic acid-d2
0 ImagesCat. No.: HY-N1902S24-Hydroxyphenylacetic acid-d2 is the deuterium labeled 4-Hydroxyphenylacetic acid (HY-N1902). 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2.
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Asulam-d3
0 ImagesCat. No.: HY-W708304Asulam-d3 is the deuterium labeled Asulam (HY-B1838). Asulam is a herbicide with control activity against wild oats. Asulam can be used for bulb production in spinach, tulips, daffodils and lilies. Maximum residue limits (MRLs) for Asulam were evaluated in spinach. The review of Asulam took into account its endocrine disrupting properties.
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4-Hydroxy ramelteon-d5
0 ImagesCat. No.: HY-W740726S4-Hydroxy ramelteon-d5 is the deuterium labeled 4-Hydroxy ramelteon.
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L-Lysine-15N2,d9 dihydrochloride
0 ImagesCat. No.: HY-W009762S5L-Lysine-15N2,d9 (dihydrochloride) is a 15N-labeled and deuterium labeled L-Lysine dihydrochloride.
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Belinostat acid-d5
0 ImagesCat. No.: HY-143924SCAS No.: 2130853-04-0Belinostat acid-d5 is the deuterium labeled Belinostat acid.
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1-Bromo-2-methoxyethane-d3
0 ImagesCat. No.: HY-W724365Synonyms: 2-Methoxyethyl Bromide-d31-Bromo-2-methoxyethane-d3 (2-Methoxyethyl Bromide-d3) is the deuterium labeled 1-Bromo-2-methoxyethane,98%(stabilized with Na2CO3).
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Bromfenac-d4 sodium
0 ImagesCat. No.: HY-B1888ASCAS No.: 2749400-35-7Bromfenac-d4 (sodium) is deuterium labeled Bromfenac (sodium). Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium is a brominated non-steroidal anti-inflammatory/analgesic agent (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME).
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L-Asparagine-13C4
0 ImagesCat. No.: HY-W017443S4CAS No.: 768348-44-3Synonyms: (-)-Asparagine-13C4; Asn-13C4; Asparamide-13C4L-Asparagine-13C4 ((-)-Asparagine-13C4; Asn-13C4) monohydrate is the 13C labeled labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
