1185241-03-5
Chemical Structure
13-cis Acitretin-d3
Synonym(s): Isoacitretin d3;Ro 13-7652 d3
- CAS No.: 1185241-03-5
- Formula:C21H23D3O3
- Molecular Weight:329.45
IUPAC Name: (2Z,4E,6E,8E)-9-(4-(methoxy-d3)-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
InChIKey: IHUNBGSDBOWDMA-ZHGFVQCVSA-N
SMILES: O=C(/C=C(\C=C\C=C(\C=C\C1=C(C=C(C(C)=C1C)OC([2H])([2H])[2H])C)C)C)O
Biological Activity: 13-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].
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13-cis Acitretin-d3 | 13-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. | |||||||||||||||||||||
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Acitretin (Standard) | ≥98% | Acitretin (Standard) is the analytical standard of Acitretin. This product is intended for research and analytical applications. Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimer’s disease. | ||||||||||||||||||||
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Acitretin | 99.62% | Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimer’s disease. | ||||||||||||||||||||
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- [1]. A E Stuck, et al. Pharmacokinetics of acitretin and its 13-cis metabolite in patients on haemodialysis. Br J Clin Pharmacol. 1989 Mar; 27(3): 301–304.
- [2]. Berbis P, et al. Residual plasma concentrations of acitretin (Ro 10-1670) and its metabolite (Ro 13-7652) after chronic administration. Dermatologica. 1988;177(4):244-6. [Content Brief]