Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

References:

[1]. Almeida B, Nag OK, Rogers KE, Delehanty JB. Recent Progress in Bioconjugation Strategies for Liposome-Mediated Drug Delivery. Molecules. 2020;25(23):5672. Published 2020 Dec 1. [Content Brief]

Liposome Related Products (1007):

By Effects:	Inhibitors (2) Controls (2) Substrate (1) Modulator (1) Chemicals (8)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-153187

LNP Lipid-4
LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances.

HY-W440823B

DSPE-PEG2000-amine sodium		99.98%
DSPE-PEG2000-amine sodium is a pegylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530), which can be used to synthesize solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.

HY-153125

DLRIE		99.41%
DLRIE is a cationic lipid that can be used for the synthesis of liposome GAP-DLRIE. GAP-DLRIE can be used to enhance the delivery and expression of plasmid DNA. DLRIE can be used for delivery of nucleic acids.

HY-115419

1-Thio-β-D-glucose sodium		99.94%
1-Thio-β-D-glucose sodium is the sodium salt form of 1-Thio-β-D-glucose. 1-Thio-β-D-glucose forms hydrophilic self-assembled monolayer with metal, stablizes the lipid bilayer and protects the proteins from denaturation.

HY-W800797

16:0 Biotinyl PE		99.36%
16:0 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.

HY-W409806

Cholesterylamine
Cholesterylamine is a cationic lipid. Cholesterylamine can be added to the PLGA to prepare PLGA particle having surface charge. Cholesterylamine can be used for drug delivery. Cholesterylamine can be used for autoimmune diseases and allergy research.

HY-177829

Liposomal Vitamin C
Liposomal Vitamin C is a specialized delivery system that encapsulates vitamin C within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of vitamin C. Vitamin C (L-ascorbic acid) is a water-soluble vit

HY-W440833

DSPE-PEG3400-azide		99.95%
DSPE-PEG3400-azide is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond.

HY-177840

Liposomal Curcumin
Liposomal Curcumin is a specialized delivery system that encapsulates curcumin within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of curcumin. Curcumin is a polyphenol compound extracted from the

HY-134174

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate		99.0%
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is a phospholipid containing saturated palmitic acid (16:0) and monounsaturated oleic acid (18:1) inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.

HY-142988

1-Stearoyl-2-myristoyl-sn-glycero-3-PC		98.0%
1-Stearoyl-2-myristoyl-sn-glycero-3-PC (1S-2M-PC) belongs to the class of asymmetric phospholipids. 1-Stearoyl-2-myristoyl-sn-glycero-3-PC is abundant in biological membranes.

HY-W590531

80-O16B		98.05%
80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP).

HY-W441013

DSPE-PEG1000-NHS
DSPE-PEG1000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG1000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG1000-NHS can be used in the study of drug delivery.

HY-W131101

Sorbitan tristearate		≥98.0%
Sorbitan tristearate is a non-ionic surfactant, with a synergistic effect on skin permeability. Sorbitan tristearate can be used as an excipient, such as emulsifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.

HY-W127350

Cholesterol Pelargonate
Cholesterol Pelargonate, a Cholesterol derivative, can be used as a triggered release liposome tested.

HY-130671A

L-DPPG
L-DPPG ((R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid targeting biological membranes. L-DPPG interacts with lipid bilayers through hydrophobic and electrostatic interactions. L-DPPG is used in research on drug delivery systems.

HY-W013063

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine		99.16%
1,2-Dilinoleoyl-sn-glycero-3-phosphocholine is a phospholipid. 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine can be used for obesity research.

HY-W440991

DOPE-PEG2000-Amine		99.86%
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.

HY-160705

PNI 132	Chemical
PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.

HY-150117

Lipid 6		99.82%
Lipid 6 is an ionizable amino lipid. Lipid 6 can be used to synthesize lipid nanoparticles. Lipid 6 can be used in RNA delivery research.

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