62600-81-1
Chemical Structure
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate
Synonym(s): 16:0-18:1 PA
- CAS No.: 62600-81-1
- Formula:C37H71O8P
- Molecular Weight:674.93
IUPAC Name: (R)-1-(palmitoyloxy)-3-(phosphonooxy)propan-2-yl oleate
InChIKey: OPVZUEPSMJNLOM-QEJMHMKOSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(O)(O)=O)COC(CCCCCCCCCCCCCCC)=O)=O
Biological Activity: 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate (16:0-18:1 PA) is an anionic phospholipid containing a monounsaturated acyl chain. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate exhibits activity in modulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is used in the preparation of micelles, liposomes, and other types of artificial membranes[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate | 99.0% | 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate (16:0-18:1 PA) is an anionic phospholipid containing a monounsaturated acyl chain. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate exhibits activity in modulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is used in the preparation of micelles, liposomes, and other types of artificial membranes. | ||||||||||||||||||||
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References
- [1]. Mansour HM, et al. The relationship between water vapor absorption and desorption by phospholipids and bilayer phase transitions. Journal of pharmaceutical sciences. 2007 Feb;96(2):377-96. [Content Brief]
- [2]. Hautala JT, et al. Anionic liposomes in capillary electrophoresis: effect of calcium on 1-palmitoyl-2-oleyl- sn-glycero-3-phosphatidylcholine / phosphatidylserine-coating in silica capillaries. Analytical and bioanalytical chemistry. 2004 Apr;378(7):1769-76.
- [3]. Laczkó-Dobos H, et al. PtdIns4P is required for the autophagosomal recruitment of STX17 (syntaxin 17) to promote lysosomal fusion. Autophagy. 2024 Jul;20(7):1639-1650.
