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Cat. No.: HY-134174

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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate

Name: 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate
Brand: MedChemExpress
SKU: HY-134174
Price: 81.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 16:0-18:1 PA)

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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate (16:0-18:1 PA) is an anionic phospholipid containing a monounsaturated acyl chain. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate exhibits activity in modulating biological membrane fluidity and participating in cell signal transduction. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is used in the preparation of micelles, liposomes, and other types of artificial membranes.

For research use only. We do not sell to patients.

Purity : 99.0%
CAS No.: 62600-81-1
Formula: C₃₇H₇₁O₈P
Molecular Weight:674.93

Storage:

Solution, -20°C, 2 years

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate Chemical Structure

CAS No.: 62600-81-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate (16:0-18:1 PA) sodium provides a negatively charged membrane environment in artificial liposomes, thereby successfully recruiting recombinant STX17 protein into the liposome layer^[1].
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate (15% phospholipid (w/w); 2-3 days) sodium exhibits a fully hydrated T_m of 24°C, a dried T_m of 70°C, and maintains a T_m value above 25°C up to 97% RH^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 62600-81-1
Appearance Liquid
Molecular Weight 674.93
Formula C₃₇H₇₁O₈P
Color Colorless to light yellow
SMILES

CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(O)(O)=O)COC(CCCCCCCCCCCCCCC)=O)=O
Synonyms

16:0-18:1 PA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years

Protocols

All Cell Biology

Directly Induced Neuron Culture
Directly induced neuron culture converts somatic cells, most commonly fibroblasts, into induced neurons without passing through a pluripotent or neural progenitor stage; classic evidence shows that mouse fibroblasts can be converted by Ascl1, Brn2/Pou3f2, and Myt1l, human fibroblasts can be converted by defined neuronal transcription factors, and human fibroblasts can also be converted by miR-9/9-124 with neurogenic or subtype-specifying transcription factors. The readout is acquisition of neuronal identity and function, assessed by neuronal morphology, neuronal markers such as Tuj1/βIII-tubulin, MAP2, synapsin, and subtype markers when relevant, together with functional assays such as action-potential firing, synaptic activity, and electrophysiology.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (585 KB)
- English - EN (585 KB)
- Français - FR (585 KB)
- Deutsch - DE (585 KB)
- Norwegian - NO (585 KB)
- Español - ES (585 KB)
- Swedish - SV (585 KB)
- Italian - IT (585 KB)
- Korean - KR (585 KB)
- Portuguese - PT (585 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mansour HM, et al. The relationship between water vapor absorption and desorption by phospholipids and bilayer phase transitions. Journal of pharmaceutical sciences. 2007 Feb;96(2):377-96. [Content Brief]

[2]. Hautala JT, et al. Anionic liposomes in capillary electrophoresis: effect of calcium on 1-palmitoyl-2-oleyl- sn-glycero-3-phosphatidylcholine / phosphatidylserine-coating in silica capillaries. Analytical and bioanalytical chemistry. 2004 Apr;378(7):1769-76.

[3]. Laczkó-Dobos H, et al. PtdIns4P is required for the autophagosomal recruitment of STX17 (syntaxin 17) to promote lysosomal fusion. Autophagy. 2024 Jul;20(7):1639-1650.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate

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Biological Activity
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate

Biological Activity

Description

In Vitro

Chemical Information

Protocols

Purity & Documentation

References

Calculators

Help & FAQs

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate Related Classifications

HY-134174 Related Classifications

Bioz

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