1. Metabolic Enzyme/Protease
  2. Phosphatase Endogenous Metabolite
  3. Tartaric acid disodium dihydrate

Tartaric acid disodium dihydrate  (Synonyms: Sodium tartrate dibasic dihydrate; Sodium tartrate dihydrate)

Cat. No.: HY-D0850 Purity: ≥98.0%
COA Handling Instructions

Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications.

For research use only. We do not sell to patients.

Tartaric acid disodium dihydrate Chemical Structure

Tartaric acid disodium dihydrate Chemical Structure

CAS No. : 6106-24-7

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 44 In-stock
Solution
10 mM * 1 mL in Water USD 44 In-stock
Solid
5 g USD 40 In-stock
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Other Forms of Tartaric acid disodium dihydrate:

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  • Biological Activity

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Description

Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications[1][2][3][4].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

L-Tartaric acid (1.66-6.64 mM) significantly reduces NEP and KCL-induced aortic ring vasoconstriction with EC50 values of 4.119 mM and 4.00 mM, respectively[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

L-Tartaric acid (80-240 mg/kg; P.O.; Single dose) reduces blood pressure in hypertensive mice induced by L-NAME (60 mg/kg) [3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Hypertensive Wistar rat model[3]
Dosage: 80 mg/kg, 240 mg/kg
Administration: Oral gavage (p.o.); Single dose. After L-NAME treatment (60.mg/kg; p.o.)
Result: Reduced systolic blood pressure (SABP) and mild blood pressure (mid-BP) in rats at a dose of 240mg/kg, but had no effect on mean artery pressure, diastolic blood pressure, pulse pressure level, and heart rate.
Molecular Weight

232.10

Formula

C4H10Na2O8

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@H](O)[C@@H](O)C(O)=O)=O.[2H2O].[2Na]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (430.85 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3085 mL 21.5424 mL 43.0849 mL
5 mM 0.8617 mL 4.3085 mL 8.6170 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 20 mg/mL (86.17 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.3085 mL 21.5424 mL 43.0849 mL 107.7122 mL
5 mM 0.8617 mL 4.3085 mL 8.6170 mL 21.5424 mL
10 mM 0.4308 mL 2.1542 mL 4.3085 mL 10.7712 mL
15 mM 0.2872 mL 1.4362 mL 2.8723 mL 7.1808 mL
20 mM 0.2154 mL 1.0771 mL 2.1542 mL 5.3856 mL
25 mM 0.1723 mL 0.8617 mL 1.7234 mL 4.3085 mL
30 mM 0.1436 mL 0.7181 mL 1.4362 mL 3.5904 mL
40 mM 0.1077 mL 0.5386 mL 1.0771 mL 2.6928 mL
50 mM 0.0862 mL 0.4308 mL 0.8617 mL 2.1542 mL
60 mM 0.0718 mL 0.3590 mL 0.7181 mL 1.7952 mL
80 mM 0.0539 mL 0.2693 mL 0.5386 mL 1.3464 mL
100 mM 0.0431 mL 0.2154 mL 0.4308 mL 1.0771 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Tartaric acid disodium dihydrate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tartaric acid disodium dihydrate
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