Tartaric acid disodium dihydrate
Based on 1 Customer Validation
Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 6106-24-7
- Formula: C4H10Na2O8
- Molecular Weight:232.10
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Microbial Metabolite |
Human Endogenous Metabolite |
L-Tartaric acid (1.66-6.64 mM) significantly reduces NEP and KCL-induced aortic ring vasoconstriction with EC50 values of 4.119 mM and 4.00 mM, respectively[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Hypertensive Wistar rat model[3]
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Dosage:80 mg/kg, 240 mg/kg
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Administration:Oral gavage (p.o.); Single dose. After L-NAME treatment (60.mg/kg; p.o.)
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Result:Reduced systolic blood pressure (SABP) and mild blood pressure (mid-BP) in rats at a dose of 240mg/kg, but had no effect on mean artery pressure, diastolic blood pressure, pulse pressure level, and heart rate.
Chemical Information
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CAS No. 6106-24-7
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Appearance Solid
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Molecular Weight 232.10
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Formula C4H10Na2O8
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Color White to off-white
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SMILES
OC([C@H](O)[C@@H](O)C(O)=O)=O.[2H2O].[2Na]
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Synonyms
Sodium tartrate dibasic dihydrate; Sodium tartrate dihydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 100 mg/mL (430.85 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 20 mg/mL (86.17 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (279 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Sasikala V, et al. Growth, molecular structure, NBO analysis and vibrational spectral analysis of l-tartaric acid single crystal. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 5;123:127-41. [Content Brief]
[2]. DeBolt S, et al. L-tartaric acid synthesis from vitamin C in higher plants. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5608-13. [Content Brief]
[3]. Amssayef A, et al. L-Tartaric Acid Exhibits Antihypertensive and Vasorelaxant Effects: The Possible Role of eNOS/NO/cGMP Pathways. Cardiovasc Hematol Agents Med Chem. 2023;21(3):202-212. [Content Brief]
[4]. EFSA Panel on Food Additives and Flavourings (FAF); Younes M, et al. Re-evaluation of l(+)-tartaric acid (E 334), sodium tartrates (E 335), potassium tartrates (E 336), potassium sodium tartrate (E 337) and calcium tartrate (E 354) as food additives. EFSA J. 2020 Mar 11;18(3):e06030. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.3085 mL | 21.5424 mL | 43.0849 mL | 107.7122 mL |
| 5 mM | 0.8617 mL | 4.3085 mL | 8.6170 mL | 21.5424 mL | |
| 10 mM | 0.4308 mL | 2.1542 mL | 4.3085 mL | 10.7712 mL | |
| 15 mM | 0.2872 mL | 1.4362 mL | 2.8723 mL | 7.1808 mL | |
| 20 mM | 0.2154 mL | 1.0771 mL | 2.1542 mL | 5.3856 mL | |
| 25 mM | 0.1723 mL | 0.8617 mL | 1.7234 mL | 4.3085 mL | |
| 30 mM | 0.1436 mL | 0.7181 mL | 1.4362 mL | 3.5904 mL | |
| 40 mM | 0.1077 mL | 0.5386 mL | 1.0771 mL | 2.6928 mL | |
| 50 mM | 0.0862 mL | 0.4308 mL | 0.8617 mL | 2.1542 mL | |
| 60 mM | 0.0718 mL | 0.3590 mL | 0.7181 mL | 1.7952 mL | |
| 80 mM | 0.0539 mL | 0.2693 mL | 0.5386 mL | 1.3464 mL | |
| 100 mM | 0.0431 mL | 0.2154 mL | 0.4308 mL | 1.0771 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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