1. Metabolic Enzyme/Protease
  2. Phosphatase

Calyculin A (Synonyms: (-)-Calyculin A)

Cat. No.: HY-18983 Purity: >98.0%
Data Sheet SDS Handling Instructions

Calyculin A is a potent inhibitor of the catalytic subunit of type-2A phosphatase, with IC50 values of 0.5 to 1 nM.

For research use only. We do not sell to patients.
Calyculin A Chemical Structure

Calyculin A Chemical Structure

CAS No. : 101932-71-2

Size Price Stock Quantity
0.5 mM * 20 uL in DMSO $80 In-stock
0.5 mM * 50 uL in DMSO $130 In-stock
0.5 mM * 200 uL in DMSO $365 In-stock
1 mg   Get quote  
5 mg   Get quote  

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Description

Calyculin A is a potent inhibitor of the catalytic subunit of type-2A phosphatase, with IC50 values of 0.5 to 1 nM. Target: protein phosphatase Calyculin A induces contraction in smooth muscle fibers. With the catalytic subunit of protein phosphatase type-1, calyculin A is an effective inhibitor , IC50 values for calyculin A is about 2 nM and. The endogenous phosphatase of smooth muscle myosin B was inhibited by calyculin A with IC50 values of 0.3 to 0.7 nM for calyculin A. The partially purified catalytic subunit from myosin B had IC50 values of 0.7 nM for calyculin A.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 0.9909 mL 4.9546 mL 9.9091 mL
5 mM 0.1982 mL 0.9909 mL 1.9818 mL
10 mM 0.0991 mL 0.4955 mL 0.9909 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1009.17

Formula

C₅₀H₈₁N₄O₁₅P

CAS No.

101932-71-2

Storage

-20°C, protect from light

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: >98.0%

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Product Name:
Calyculin A
Cat. No.:
HY-18983
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