1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Brimonidine tartrate

Brimonidine tartrate (Synonyms: UK 14304 tartrate; AGN190342 tartrate)

Cat. No.: HY-B0659A Purity: 99.19%
Handling Instructions

Brimonidine tartrate (UK 14304 tartrate) is a full α2-adrenergic receptor (α2-AR) agonist.

For research use only. We do not sell to patients.

Brimonidine tartrate Chemical Structure

Brimonidine tartrate Chemical Structure

CAS No. : 70359-46-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
500 mg USD 150 In-stock
Estimated Time of Arrival: December 31
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5 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Brimonidine tartrate:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Brimonidine tartrate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Brimonidine tartrate (UK 14304 tartrate) is a full α2-adrenergic receptor (α2-AR) agonist.

IC50 & Target

α2-adrenergic Receptor[1].

In Vitro

[3H]Brimonidine (UK 14304) is a full agonist at alpha 2-adrenergic receptors. [3H]Brimonidine (UK 14304) labels at least 2 specific binding sites in human brain that both have the characteristics of an alpha 2-adrenergic binding site. GTP decreases agonist binding at both of these sites, but with different potencies at each site [1-3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

442.22

Formula

C₁₅H₁₆BrN₅O₆

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (113.07 mM; Need ultrasonic)

H2O : 25 mg/mL (56.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2613 mL 11.3066 mL 22.6132 mL
5 mM 0.4523 mL 2.2613 mL 4.5226 mL
10 mM 0.2261 mL 1.1307 mL 2.2613 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (226.13 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.65 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.65 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Brimonidine tartrate
Cat. No.:
HY-B0659A
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