1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Brimonidine

Brimonidine (Synonyms: UK 14304; AGN190342)

Cat. No.: HY-B0659 Purity: 99.99%
Handling Instructions

Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist.

For research use only. We do not sell to patients.

Brimonidine Chemical Structure

Brimonidine Chemical Structure

CAS No. : 59803-98-4

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 66 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 101 In-stock
Estimated Time of Arrival: December 31
50 mg USD 392 In-stock
Estimated Time of Arrival: December 31
100 mg USD 702 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Brimonidine:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Brimonidine

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist.

IC50 & Target

α2-adrenergic Receptor.

In Vitro

[3H]Brimonidine (UK 14304) is a full agonist at alpha 2-adrenergic receptors. [3H]Brimonidine (UK 14304) labels at least 2 specific binding sites in human brain that both have the characteristics of an alpha 2-adrenergic binding site. GTP decreases agonist binding at both of these sites, but with different potencies at each site [1-3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

292.13

Formula

C₁₁H₁₀BrN₅

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (171.16 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4231 mL 17.1157 mL 34.2313 mL
5 mM 0.6846 mL 3.4231 mL 6.8463 mL
10 mM 0.3423 mL 1.7116 mL 3.4231 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.56 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.56 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 2.5 mg/mL (8.56 mM); Clear solution; Need warming

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Brimonidine
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HY-B0659
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