1. Neuronal Signaling
    Stem Cell/Wnt
  2. γ-secretase
  3. Aβ42-IN-2

Aβ42-IN-2 

Cat. No.: HY-136866 Purity: 98.14%
Handling Instructions

Aβ42-IN-2 is a γ-secretase modulators extracted from patent WO2016070107, compound example example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 can be used for the research of a disorder associated with aberrant A3 peptide levels, including Alzheimer's disease.

For research use only. We do not sell to patients.

Aβ42-IN-2 Chemical Structure

Aβ42-IN-2 Chemical Structure

CAS No. : 1914989-80-2

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 385 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2550 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Aβ42-IN-2 is a γ-secretase modulators extracted from patent WO2016070107, compound example example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 can be used for the research of a disorder associated with aberrant A3 peptide levels, including Alzheimer's disease[1].

IC50 & Target

Αβ42[1]

Molecular Weight

430.50

Formula

C₂₄H₂₆N₆O₂

CAS No.

1914989-80-2

SMILES

CC1=CC(C2=NC(OC)=C(N3C=C(C)N=C3)C=C2)=NN=C1N[[email protected]](C4=CC=C(OC)C=C4)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (RT, stored under nitrogen)

References
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Keywords:

Aβ42-IN-2γ-secretaseGamma secretaseAβ42Alzheimer'sdiseaseADInhibitorinhibitorinhibit

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Aβ42-IN-2
Cat. No.:
HY-136866
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