2. Metabolic Enzyme/Protease
  3. Aldehyde Dehydrogenase (ALDH)
  4. ALDH1A1-IN-2

ALDH1A1-IN-2 (compound 297) is a potent inhibitor of aldehyde dehydrogenase 1a1 (aldh1a1). Aldehyde dehydrogenases (ALDH) constitute a family of enzymes that play a critical role in oxidizing various cytotoxic xenogenic and biogenic aldehydes. ALDH1A1-IN-2 has the potential for the research of cancer, inflammation, or obesity.

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ALDH1A1-IN-2

ALDH1A1-IN-2 Estructura química

No. CAS : 2231081-18-6

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5 mg En stock
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500 mg   Obtener un presupuesto  

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ALDH1A1-IN-2 Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas Aldehyde Dehydrogenase (ALDH):

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ALDH1 ALDH2 ALDH3

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Descripciòn

ALDH1A1-IN-2 (compound 297) is a potent inhibitor of aldehyde dehydrogenase 1a1 (aldh1a1). Aldehyde dehydrogenases (ALDH) constitute a family of enzymes that play a critical role in oxidizing various cytotoxic xenogenic and biogenic aldehydes. ALDH1A1-IN-2 has the potential for the research of cancer, inflammation, or obesity[1].

IC50 & Target

ALDH1

 

Peso molecular

494.99

Fòrmula

C25H23ClN4O3S
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

N#CC1(C2=CC=C(C3=C(C(N4CCN(S(=O)(C)=O)CC4)=O)C=NC5=CC=C(Cl)C=C35)C=C2)CC1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 1 mg/mL (2.02 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0202 mL 10.1012 mL 20.2024 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0202 mL 10.1012 mL 20.2024 mL 50.5061 mL
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ALDH1A1-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALDH1A1-IN-22231081-18-6Aldehyde Dehydrogenase (ALDH)aldh1a1Aldehyde dehydrogenasescancerinflammationobesitycytotoxic xenogenicbiogenic aldehydesInhibitorinhibitorinhibit

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Nombre del producto:
ALDH1A1-IN-2
Cat. No.:
HY-126003
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