AF488-conjugated MHC ClassII (I-A/I-E) Antibody (M5/114)
(Synonyms: MHC ClassII (I-A/I-E),IA-IE-AF488,M5/114)AF488-conjugated MHC ClassII (I-A/I-E) Antibody (M5/114) is a Rat-derived and AF488 conjugated monoclonal antibody, targeting to MHC ClassII (I-A/I-E).
-
Host:
Rat
-
Isotype:
Rat IgG2b,κ
-
Application:
FC
-
Reactivity :
Mouse
-
Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
-
Conjugation:
AF488
Applications
| Application |
FC
FC: Flow Cytometry
|
|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
-
Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
-
Shipping
Shipping with blue ice.
Background
-
Function
MHC Class II (I-A/I-E) molecules are central components of the mouse antigen-presentation system, comprising the I-A and I-E subclasses; they are primarily expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. By presenting exogenous antigenic peptides to CD4+ T cells, they initiate and regulate adaptive immune responses, serving as key markers for studying APC activation, macrophage polarization, infection immunity, tumor immunity, and autoimmune diseases.
-
Isoforms & Post-Translational Modification
.
-
Synonyms
MHC ClassII (I-A/I-E),IA-IE-AF488,M5/114
Documentation