CD1C Antibody (YA2986)
(Synonyms: CD1C; T-cell surface glycoprotein CD1c; CD1c)CD1C Antibody (YA2986) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD1C.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
CD1C Antibody (YA2986) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD1C.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 38 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 38 kDa
A synthesized peptide derived from human CD1c aa100-169.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD1C belongs to Group 1 of the transmembrane glycoprotein CD1 family. CD1C protein, as a key antigen-presenting molecule, has shown the ability to bind both self and non-self lipid and glycolipid antigens, mediating host defense against tuberculosis. CD1C is associated with breast cancer prognosis and immune invasion. CD1C-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His) is a recombinant protein dimer complex containing Rhesus Macaque-derived CD1C-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag. CD1C-B2M Heterodimer Protein, Rhesus Macaque (HEK293, His), has molecular weight of ~44.7 (33.1+ 11.6) KDa.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Endosome membrane; Single-pass type I membrane protein; Lysosome
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Expression
Tissue_specificity:It is expressed in cortical thymocytes, certain T-cell leukemias, and various other tissues. -
Subunit
Heterodimer with B2M (beta-2-microglobulin)
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SwissProt ID
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Synonyms
CD1C; T-cell surface glycoprotein CD1c; CD1c
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Research Field
Immunology
Documentation