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Macrophage mannose receptor 1 Antibody (YA3891)

(Synonyms: MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1)
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Based on 1 Customer Validation

Macrophage mannose receptor 1 Antibody (YA3891) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Macrophage mannose receptor 1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3891)
  • Macrophage mannose receptor 1 Antibody (YA3891) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:200-1:1000 1:200-1:400

Product Details

Description

Macrophage mannose receptor 1 Antibody (YA3891) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Macrophage mannose receptor 1.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 166 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 166 kDa
Immunogen

Purified recombinant fragment of human CD206 (AA: extra(19-218)) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3891)
    Flow cytometric analysis of 1X106 HepG2 cells labeling Macrophage mannose receptor 1 Antibody (HY-P84194, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/400 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Mouse IgG H&L (HY-P8005) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Mouse IgG Isotype Control (HY-P80757, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

Background

  • Function

    Macrophage mannose receptor 1 mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains; (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens; (Microbial infection) Acts as a receptor for Dengue virus envelope protein E; (Microbial infection) Interacts with Hepatitis B virus envelope protein

  • Subcellular Localization

    Endosome membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein

  • Isoforms & Post-Translational Modification

    P22897 has 2 isomers: P22897-1: 166012 Da (predicted); P22897-2: 56554 Da (predicted).

  • Subunit

    (Microbial infection) Interacts with Dengue virus

  • SwissProt ID

    P22897

  • Gene ID
    4360 [NCBI]
  • Synonyms

    MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1

Macrophage mannose receptor 1 Antibody (YA3891) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Flow cytometric analysis of 1X106 HepG2 cells labeling Macrophage mannose receptor 1 Antibody (HY-P84194, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/400 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Mouse IgG H&L (HY-P8005) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Mouse IgG Isotype Control (HY-P80757, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Macrophage mannose receptor 1 Antibody (YA3891) Product Image
    1/16
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3891)
  • Macrophage mannose receptor 1 Antibody (YA3891) Product Image
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3891)
    1/1
    MedChemExpress Validation
     Flow cytometric analysis of 1X106 HepG2 cells labeling Macrophage mannose receptor 1 Antibody (HY-P84194, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/400 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Mouse IgG H&L (HY-P8005) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Mouse IgG Isotype Control (HY-P80757, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Experimental Validation Results for Macrophage mannose receptor 1 Antibody (YA3891)
  • Macrophage mannose receptor 1 Antibody (YA3891) Product Image
    MedChemExpress Validation

    Flow cytometric analysis of 1X106 HepG2 cells labeling Macrophage mannose receptor 1 Antibody (HY-P84194, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/400 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Mouse IgG H&L (HY-P8005) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Mouse IgG Isotype Control (HY-P80757, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Macrophage mannose receptor 1 Antibody (YA3891) Product Image FC