MNDA Antibody (YA7850)(PBS only)
(Synonyms: PYHIN3)MNDA Antibody (YA7850) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MNDA.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
MNDA Antibody (YA7850) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MNDA.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 45.7 kDa
Human recombinant protein fragment corresponding to amino acids 37-321 of human MNDA produced in E.coli.
Affinity purified
Non-conjugated
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MNDA may act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1
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Subcellular Localization
Nucleus,Cytoplasm
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Expression
Tissue_Specificity: Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appears in myeloblast cells in some cases of acute myeloid Leukemia
Induction: Strongly induced by alpha interferon which selectively affects expression in late stage cells in the monocytic but not the granulocytic lineage. Induced in vitro by dimethylsulfoxide and 1,25 dihydroxyvitamin D3 -
Isoforms & Post-Translational Modification
P41218: 407 amino acids, molecular weight 45836 Da.
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Subunit
Participates in a ternary complex with YY1 and the YY1 target DNA element
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SwissProt ID
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Synonyms
PYHIN3
Documentation
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