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  3. Monoclonal Antibodies Recombinant Antibodies
  4. PCPTP1 Antibody (YA1549)

PCPTP1 Antibody (YA1549)

Cat. No.: HY-P81804
User Guide for Antibodies Technical Support

PCPTP1 Antibody (YA1549) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PCPTP1.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • Documentation

Description

PCPTP1 Antibody (YA1549) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PCPTP1.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight
Predicted band size: 74 kDa;
Observed band size: 74 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human PCPTP1

Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background
Function:Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity)
Subcellular Localization:Secreted; Cell membrane; Single-pass type I membrane protein; Cytoplasm, perinuclear region; Cytoplasm, perinuclear region
Expression:
Tissue_specificity:Detected in cerebrospinal fluid (at protein level) (PubMed:25326458) . Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus
Isoforms & Post-Translational Modification:Q15256 has 4 isomers: Q15256-1: 73834 Da (predicted); Q15256-3: 46581 Da (predicted); Q15256-4: 51046 Da (predicted); Q15256-5: 61415 Da (predicted).
Subunit:Interacts with MAPKs
Database

Entrez Gene: 94202 Rat

SwissProt: O08617 

Research Field

Signal Transduction

Synonyms
PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7
Documentation

PCPTP1 Antibody (YA1549) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PCPTP1 Antibody (YA1549)
Cat. No.:
HY-P81804
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