TN-X Antibody (YA1237)
(Synonyms: Tenascin X; TNXB; XB; TNX; XBS; HXBL; TENX; TN-X; TNXB1; TNXB2; Tenascin-X)TN-X Antibody (YA1237) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TN-X.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.108.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
TN-X Antibody (YA1237) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TN-X.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 75/140 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 458 kDa
A synthesized peptide derived from human TNXB
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.108.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TN-X is an Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors
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Subcellular Localization
Secreted, extracellular space, extracellular matrix
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Expression
Tissue_specificity:Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB-short is only expressed in the adrenal gland -
Isoforms & Post-Translational Modification
P22105 has 4 isomers: P22105-3: 458388 Da (predicted); P22105-1: 458220 Da (predicted); P22105-2: 74030 Da (predicted); P22105-4: 458535 Da (predicted).
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Subunit
Homotrimer. Interacts with type I, III and V collagens and tropoelastin via its 29th fibronectin type-III domain
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SwissProt ID
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Synonyms
Tenascin X; TNXB; XB; TNX; XBS; HXBL; TENX; TN-X; TNXB1; TNXB2; Tenascin-X
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Research Field
Signal Transduction
Documentation