Antrafenine dihydrochloride
Antrafenine (Stakane) dihydrochloride is a non-narcotic analgesic. Antrafenine dihydrochloride demonstrates central analgesic effects in acetic acid writhing test and mouse hot plate test experiments. Antrafenine dihydrochloride significantly alleviates osteoarthritis pain. Antrafenine dihydrochloride exhibits mild anti-inflammatory activity in a rat toe edema model. Antrafenine dihydrochloride can be used for pain and anti-inflammatory research.
For research use only. We do not sell to patients.
- CAS No.: 55300-30-6
- Formula: C30H28Cl2F6N4O2
- Molecular Weight:661.47
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
CAS No. 55300-30-6
-
Molecular Weight 661.47
-
Formula C30H28Cl2F6N4O2
-
SMILES
O=C(C1=CC=CC=C1NC2=C3C=CC(C(F)(F)F)=CC3=NC=C2)OCCN4CCN(C5=CC=CC(C(F)(F)F)=C5)CC4.Cl.Cl
-
Synonyms
Stakane dihydrochloride
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Manoury PM, et al. Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates. J Med Chem. 1979;22(5):554-559. [Content Brief]
[2]. Berry H, et al. Antrafenine, naproxen and placebo in osteoarthritis: a comparative study. Br J Rheumatol. 1983 May;22(2):89-94. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)