Ara-F-NAD+ sodium
Based on 1 Customer Validation
Ara-F-NAD+ sodium is an arabino analogue of NAD+. Ara-F-NAD+ sodium is a potent, reversible and slow-binding CD38 NADase inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.59%
- Formula: C21H25FN7NaO13P2
- Molecular Weight:687.40
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 687.40
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Formula C21H25FN7NaO13P2
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Color White to off-white
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SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OC[C@@H]4[C@@H](O)[C@H](F)[C@H]([N+]5=CC=CC(C(N)=O)=C5)O4)([O-])=O)(O[Na])=O)O3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 125 mg/mL (181.84 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Berthelier V, et al. Human CD38 is an authentic NAD(P)+ glycohydrolase. Biochem J. 1998;330 ( Pt 3)(Pt 3):1383-1390. [Content Brief]
[2]. Wang S, et al. Design, synthesis and SAR studies of NAD analogues as potent inhibitors towards CD38 NADase. Molecules. 2014;19(10):15754-15767. Published 2014 Sep 29. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.4548 mL | 7.2738 mL | 14.5476 mL | 36.3689 mL |
| 5 mM | 0.2910 mL | 1.4548 mL | 2.9095 mL | 7.2738 mL | |
| 10 mM | 0.1455 mL | 0.7274 mL | 1.4548 mL | 3.6369 mL | |
| 15 mM | 0.0970 mL | 0.4849 mL | 0.9698 mL | 2.4246 mL | |
| 20 mM | 0.0727 mL | 0.3637 mL | 0.7274 mL | 1.8184 mL | |
| 25 mM | 0.0582 mL | 0.2910 mL | 0.5819 mL | 1.4548 mL | |
| 30 mM | 0.0485 mL | 0.2425 mL | 0.4849 mL | 1.2123 mL | |
| 40 mM | 0.0364 mL | 0.1818 mL | 0.3637 mL | 0.9092 mL | |
| 50 mM | 0.0291 mL | 0.1455 mL | 0.2910 mL | 0.7274 mL | |
| 60 mM | 0.0242 mL | 0.1212 mL | 0.2425 mL | 0.6061 mL | |
| 80 mM | 0.0182 mL | 0.0909 mL | 0.1818 mL | 0.4546 mL | |
| 100 mM | 0.0145 mL | 0.0727 mL | 0.1455 mL | 0.3637 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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