1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
  2. Histamine Receptor
  3. Betazole dihydrochloride

Betazole dihydrochloride (Synonyms: Ametazole dihydrochloride)

Cat. No.: HY-B1557A
Handling Instructions

Betazole (Ametazole) dihydrochloride, a pyrazole analogue of histamine, is an orally active H2 receptor agonist. Betazole dihydrochloride induces gastric acid secretion, and causes an immediate and significant increase in common bile duct pressure. Betazole dihydrochloride has been used as a diagnostic agent known as histalog, for investigating gastric acid secretory capacity.

For research use only. We do not sell to patients.

Betazole dihydrochloride Chemical Structure

Betazole dihydrochloride Chemical Structure

CAS No. : 138-92-1

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Description

Betazole (Ametazole) dihydrochloride, a pyrazole analogue of histamine, is an orally active H2 receptor agonist. Betazole dihydrochloride induces gastric acid secretion, and causes an immediate and significant increase in common bile duct pressure. Betazole dihydrochloride has been used as a diagnostic agent known as histalog, for investigating gastric acid secretory capacity[1][2][3].

IC50 & Target[1]

H2 Receptor

 

In Vitro

Betazole (Ametazole) dihydrochloride is a weak histamine agonist with relative selectivity towards H2 receptors and only minimal H1 activity. Betazole dihydrochloride induces gastric inhibitory polypeptide (GIP) secretion[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

184.07

Formula

C₅H₁₁Cl₂N₃

CAS No.

138-92-1

SMILES

NCCC1=NNC=C1.[H]Cl.[H]Cl

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

BetazoleAmetazoleHistamine ReceptorhistaloggastricacidsecretionbileductpressuresecretorycapacityInhibitorinhibitorinhibit

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Betazole dihydrochloride
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HY-B1557A
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