Keratin, type I cytoskeletal 25

Definition:

Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization.

References:

[1]. Nikolay V Zernov, et al. Autosomal Recessive Hypotrichosis with Woolly Hair Caused by a Mutation in the Keratin 25 Gene Expressed in Hair Follicles. J Invest Dermatol. 2016 Jun;136(6):1097-1105. [Content Brief]

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