Nuclear envelope pore membrane protein POM 121C

Definition:

Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).

References:

[1]. Tomoko Funakoshi, et al. Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes. FEBS Lett. 2007 Oct 16;581(25):4910-6. [Content Brief]

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