Butyne-DOTA-tris(t-butyl ester)
Based on 1 Customer Validation
Butyne-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.
For research use only. We do not sell to patients.
- Purity : 98.51%
- CAS No.: 2125661-54-1
- Formula: C32H57N5O7
- Molecular Weight:623.82
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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HY-133540
Maleimide-DOTA -
HY-100138
2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) -
HY-48876
p-NH2-Bn-DOTA -
HY-W782078
Butyne-DOTA -
HY-134797
p-SCN-Bn-deferoxamine -
HY-W678394
DOTA-Thiol -
HY-W614269
DOTA-GA(tBu)4 -
HY-W087027
Maleimide-NOTA -
HY-132989
Mal-Deferoxamine -
HY-W749603
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) -
HY-156035
Bz-DTPA -
HY-W717743
DOTAM-mono-acid
All Radionuclide-Drug Conjugates (RDCs) Isoforms
More
Biological Activity
Description
IC50 & Target
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RDC Bifunctional Chelator |
Chemical Information
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CAS No. 2125661-54-1
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Appearance Solid
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Molecular Weight 623.82
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Formula C32H57N5O7
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Color White to off-white
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SMILES
O=C(CN1CCN(CCN(CCN(CC1)CC(OC(C)(C)C)=O)CC(NCCC#C)=O)CC(OC(C)(C)C)=O)OC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (80.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6030 mL | 8.0151 mL | 16.0303 mL | 40.0757 mL |
| 5 mM | 0.3206 mL | 1.6030 mL | 3.2061 mL | 8.0151 mL | |
| 10 mM | 0.1603 mL | 0.8015 mL | 1.6030 mL | 4.0076 mL | |
| 15 mM | 0.1069 mL | 0.5343 mL | 1.0687 mL | 2.6717 mL | |
| 20 mM | 0.0802 mL | 0.4008 mL | 0.8015 mL | 2.0038 mL | |
| 25 mM | 0.0641 mL | 0.3206 mL | 0.6412 mL | 1.6030 mL | |
| 30 mM | 0.0534 mL | 0.2672 mL | 0.5343 mL | 1.3359 mL | |
| 40 mM | 0.0401 mL | 0.2004 mL | 0.4008 mL | 1.0019 mL | |
| 50 mM | 0.0321 mL | 0.1603 mL | 0.3206 mL | 0.8015 mL | |
| 60 mM | 0.0267 mL | 0.1336 mL | 0.2672 mL | 0.6679 mL | |
| 80 mM | 0.0200 mL | 0.1002 mL | 0.2004 mL | 0.5009 mL |
Butyne-DOTA-tris(t-butyl ester) Related Classifications
HY-W451440 Related Classifications
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