Lofemizole
Based on 1 Customer Validation
Lofemizole is a non-steroidal anti-inflammatory agent.
For research use only. We do not sell to patients.
- Purity : 99.84%
- CAS No.: 65571-68-8
- Formula: C10H9ClN2
- Molecular Weight:192.64
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Chemical Information
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CAS No. 65571-68-8
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Appearance Solid
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Molecular Weight 192.64
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Formula C10H9ClN2
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SMILES
CC1=C(C2=CC=C(Cl)C=C2)NC=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (259.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Marzo A, et al. Gas-liquid chromatographic evaluation of lofemizole in biological samples for pharmacokinetic investigations Comparison of two analytical methods[J]. Journal of Chromatography B: Biomedical Sciences and Applications, 1984, 310: 51-59. [Content Brief]
[2]. Marzo A, et al., Gas--liquid chromatographic evaluation of lofemizole in biological samples for pharmacokinetic investigations. Comparison of two analytical methods. J Chromatogr. 1984 Sep 14;310(1):51-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1910 mL | 25.9551 mL | 51.9103 mL | 129.7757 mL |
| 5 mM | 1.0382 mL | 5.1910 mL | 10.3821 mL | 25.9551 mL | |
| 10 mM | 0.5191 mL | 2.5955 mL | 5.1910 mL | 12.9776 mL | |
| 15 mM | 0.3461 mL | 1.7303 mL | 3.4607 mL | 8.6517 mL | |
| 20 mM | 0.2596 mL | 1.2978 mL | 2.5955 mL | 6.4888 mL | |
| 25 mM | 0.2076 mL | 1.0382 mL | 2.0764 mL | 5.1910 mL | |
| 30 mM | 0.1730 mL | 0.8652 mL | 1.7303 mL | 4.3259 mL | |
| 40 mM | 0.1298 mL | 0.6489 mL | 1.2978 mL | 3.2444 mL | |
| 50 mM | 0.1038 mL | 0.5191 mL | 1.0382 mL | 2.5955 mL | |
| 60 mM | 0.0865 mL | 0.4326 mL | 0.8652 mL | 2.1629 mL | |
| 80 mM | 0.0649 mL | 0.3244 mL | 0.6489 mL | 1.6222 mL | |
| 100 mM | 0.0519 mL | 0.2596 mL | 0.5191 mL | 1.2978 mL |