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Cat. No.: HY-117198

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CHIR-21208

CHIR-21208 is a highly selective glycogen synthase kinase-3 (GSK-3) inhibitor. CHIR-21208 is promising for research of neurodegenerative disorders like Alzheimer's disease and type 2 diabetes.

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CAS No.: 206275-65-2
Formule: C₁₉H₂₀F₃N₇O₃
Masse moléculaire:451.41

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CHIR-21208 Chemical Structure

CAS No.: 206275-65-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

CHIR-21208 is a highly selective glycogen synthase kinase-3 (GSK-3) inhibitor. CHIR-21208 is promising for research of neurodegenerative disorders like Alzheimer's disease and type 2 diabetes^[1].

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Chemical Information

CAS No. 206275-65-2
Masse moléculaire 451.41
Formule C₁₉H₂₀F₃N₇O₃
SMILES

O=C(N)CN(C=1N=C(NCC2=CC=C(C=C2)C(F)(F)F)C=3N=CN(C3N1)C)C(=O)COC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Peter Schultz, et al. Purine inhibitors of glycogen synthase kinase 3 (gsk3). WO1998016528A1. 1998-04-23.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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CHIR-21208

Voir tous les produits spécifiques à Isoform GSK-3

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CHIR-21208 Related Classifications

HY-117198 Related Classifications