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SIK-IN-2

SIK-IN-2 (Compound 45) is an inhibitor for salt-inducible kinase (SIK), which inhibits SKI1, SIK2 and SIK3 with IC50s of 0.1, 0.2 and 0.4 nM, respectively. SIK-IN-2 inhibits the release of TNFa with IC50 of 0.5 nM, stimulates the LPS (HY-D1056) -induced IL-10 release with EC50 of 2 nM in human macrophages.

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  • CAS No.: 3033846-20-4
  • Formule: C22H22N6OS
  • Masse moléculaire:418.51
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SIK-IN-2 Chemical Structure
    SIK-IN-2 Chemical Structure
CAS No.: 3033846-20-4
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  • SIK-IN-2 Chemical Structure
    SIK-IN-2 Chemical Structure
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  • SIK-IN-2