1052646-54-4
1052646-54-4
Chemical Structure
Antiproliferative agent-72
- CAS No.: 1052646-54-4
- Formula:C20H17Cl2N3O2S
- Molecular Weight:434.34
InChIKey: FLKKRILCGIEOOD-UHFFFAOYSA-N
SMILES: ClC1=CC(Cl)=C2C=C1OCCCCOC3=CC=CC(SC4=NC(N)=NC2=C4)=C3
Biological Activity: Antiproliferative agent-72 (Compound 10) is a Hsp90 inhibitor with a Kd of 11 nM. Antiproliferative agent-72 has antiproliferative activity with IC50s of 1.5 μM and 1.1 μM for HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 can be used for cancers research[1].
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Antiproliferative agent-72 | Antiproliferative agent-72 (Compound 10) is a Hsp90 inhibitor with a Kd of 11 nM. Antiproliferative agent-72 has antiproliferative activity with IC50s of 1.5 μM and 1.1 μM for HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 can be used for cancers research. | |||||||||||||||||||||
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