115404-57-4
Chemical Structure
Niloticin
- CAS No.: 115404-57-4
- Formula:C30H48O3
- Molecular Weight:456.70
IUPAC Name: (5R,9R,10R,13S,14S,17S)-17-((2S,4R)-4-((S)-3,3-dimethyloxiran-2-yl)-4-hydroxybutan-2-yl)-4,4,10,13,14-pentamethyl-1,2,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: GKQMMZUXYRXFOH-QBLSGNHRSA-N
SMILES: C[C@@]1(CC[C@@]2([H])[C@@H](C)C[C@H]([C@@](O3)([H])C3(C)C)O)C([C@]4([H])CC[C@]12C)=CC[C@](C(C)5C)([H])[C@@]4(CCC5=O)C
Biological Activity: Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1].
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Niloticin | 98.0% | Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. | ||||||||||||||||||||
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Keywords
