1245814-52-1

STAT3-IN-17 Chemical Structure
1245814-52-1

Chemical Structure

STAT3-IN-17

  • CAS No.: 1245814-52-1
  • Formula:C11H6F3N3O3S
  • Molecular Weight:317.24

IUPAC Name: N-(5-nitrothiazol-2-yl)-4-(trifluoromethyl)benzamide

InChIKey: HKCGJKNZQDBZFT-UHFFFAOYSA-N

SMILES: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C(C(F)(F)F)C=C2

Biological Activity: STAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori[1][2].

Cat. No. Product Name Purity Description Pricing
HY-148706 		STAT3-IN-17 98.0% STAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori.
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