1245814-52-1
1245814-52-1
Chemical Structure
STAT3-IN-17
- CAS No.: 1245814-52-1
- Formula:C11H6F3N3O3S
- Molecular Weight:317.24
IUPAC Name: N-(5-nitrothiazol-2-yl)-4-(trifluoromethyl)benzamide
InChIKey: HKCGJKNZQDBZFT-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C(C(F)(F)F)C=C2
Biological Activity: STAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori[1][2].
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STAT3-IN-17 | 98.0% | STAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori. | ||||||||||||||||||||
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