132392-39-3
Chemical Structure
LY221068
- CAS No.: 132392-39-3
- Formula:C20H30N2O2S
- Molecular Weight:362.53
IUPAC Name: (Z)-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)-3-(dimethylamino)thiazolidin-4-one
InChIKey: DNXBQWAKVPAADQ-WJDWOHSUSA-N
SMILES: O=C1N(CS/C1=C\C2=CC(C(C)(C)C)=C(C(C(C)(C)C)=C2)O)N(C)C
Biological Activity: LY221068 is an anti-oxidant and an orally active, potent inhibitor of iron-dependent lipid peroxidation and 5-lipoxygenase with antiinflammatory properties. LY221068 inhibits bone damage and paw swelling in the Freund's Complete adjuvant (HY-153808) induced arthritis (FCA) model of rats. LY221068 is promising for research of arthritis[1].
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LY221068 | LY221068 is an anti-oxidant and an orally active, potent inhibitor of iron-dependent lipid peroxidation and 5-lipoxygenase with antiinflammatory properties. LY221068 inhibits bone damage and paw swelling in the Freund's Complete adjuvant (HY-153808) induced arthritis (FCA) model of rats. LY221068 is promising for research of arthritis. | |||||||||||||||||||||
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Keywords