132723-01-4
132723-01-4
Chemical Structure
Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside
- CAS No.: 132723-01-4
- Formula:C24H19FN4O5
- Molecular Weight:462.43
IUPAC Name: ((2R,3R,4S,5R)-3-(benzoyloxy)-4-fluoro-5-(9H-purin-9-yl)tetrahydrofuran-2-yl)methyl benzoate
InChIKey: YXTKFKCWDQPVRO-XAPVIXHLSA-N
SMILES: F[C@H]1[C@H](OC(C2=CC=CC=C2)=O)[C@@H](COC(C3=CC=CC=C3)=O)O[C@H]1N4C(N=CN=C5)=C5N=C4
Biological Activity: Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside | Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
