14599-46-3
14599-46-3
Chemical Structure
5-Carboxy-2′-deoxyuridine
- CAS No.: 14599-46-3
- Formula:C10H12N2O7
- Molecular Weight:272.21
IUPAC Name: 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
InChIKey: GAGYTXTVUMXAOC-RRKCRQDMSA-N
SMILES: O[C@H]1C[C@H](N2C(NC(C(C(O)=O)=C2)=O)=O)O[C@@H]1CO
Biological Activity: 5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine[1]. 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine[2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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5-Carboxy-2′-deoxyuridine | 99.28% | 5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine. 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine. | ||||||||||||||||||||
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5-Carboxy-2′-deoxyuridine (Standard) | ≥98% | 5-Carboxy-2′-deoxyuridine (Standard) is the analytical standard of 5-Carboxy-2′-deoxyuridine. This product is intended for research and analytical applications. 5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine. 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine. | ||||||||||||||||||||
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References
- [1]. V Guerniou, et al. New synthesis of 5-carboxy-2'-deoxyuridine and its incorporation into synthetic oligonucleotides. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1073-5. [Content Brief]
- [2]. D Pavan-Langston, et al. Intraocular penetration of trifluridine. Am J Ophthalmol. 1979 Jun;87(6):814-8. [Content Brief]
