150693-65-5
Chemical Structure
Lagunamycin
- CAS No.: 150693-65-5
- Formula:C19H21N3O4
- Molecular Weight:355.39
IUPAC Name: (R,E)-6-diazo-4-(4,6-dimethylhept-2-en-2-yl)-3-methylquinoline-2,5,7,8(1H,6H)-tetraone
InChIKey: PJKDXVRDJPKOHU-YIXGCBLDSA-N
SMILES: O=C1NC2=C(C(C(C(C2=O)=O)=[N+]=[N-])=O)C(/C(C)=C/[C@H](C)CC(C)C)=C1C
Biological Activity: Lagunamycin is a 5-lipoxygenase inhibitor isolated from the culture medium of Streptomyces sp. AA0310. Lagunamycin has a significant inhibitory activity against rat 5-lipoxygenase with an IC50 value of 6.08 μM. Lagunamycin can effectively inhibit 5-lipoxygenase without causing lipid peroxidation, indicating that it has an effective inhibitory effect without causing side effects.
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Lagunamycin | Lagunamycin is a 5-lipoxygenase inhibitor isolated from the culture medium of Streptomyces sp. AA0310. Lagunamycin has a significant inhibitory activity against rat 5-lipoxygenase with an IC50 value of 6.08 μM. Lagunamycin can effectively inhibit 5-lipoxygenase without causing lipid peroxidation, indicating that it has an effective inhibitory effect without causing side effects. | |||||||||||||||||||||
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