1848224-71-4
1848224-71-4
Chemical Structure
Tivanisiran
Synonym(s): SYL1001
- CAS No.: 1848224-71-4
- Formula:N/A
- Molecular Weight:12068.30 (AS: 5294.6 + SS: 6125.7)
SMILES: [Tivanisiran]
Biological Activity: Tivanisiran (SYL1001) is a small interfering RNA (siRNA) targeting TRPV1 . Tivanisiran induces the degradation of TRPV1 mRNA, thereby inhibiting protein synthesis. Tivanisiran alleviates ocular discomfort and pain, and improves ocular hyperemia and tear quality. Tivanisiran is applicable to research related to dry eye disease[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tivanisiran | 97.48% | Tivanisiran (SYL1001) is a small interfering RNA (siRNA) targeting TRPV1 . Tivanisiran induces the degradation of TRPV1 mRNA, thereby inhibiting protein synthesis. Tivanisiran alleviates ocular discomfort and pain, and improves ocular hyperemia and tear quality. Tivanisiran is applicable to research related to dry eye disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Moreno-Montañés J, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018;27(4):421-426. [Content Brief]
- [2]. Ruz V, et al. Clinical Results of tivanisiran, a siRNA for the treatment of dry eye disease[J]. Investigative Ophthalmology & Visual Science, 2019, 60(9): 6738-6738.
Keywords
