1888305-85-8
1888305-85-8
Chemical Structure
ERK5-IN-3
- CAS No.: 1888305-85-8
- Formula:C24H23Cl2FN4O2
- Molecular Weight:489.37
IUPAC Name: 4-(3,6-dichloro-2-fluorobenzoyl)-N-(6-((1-methylpiperidin-4-yl)methyl)pyridin-3-yl)-1H-pyrrole-2-carboxamide
InChIKey: BSXWVGKWFWOEKW-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C(C2=C(Cl)C=CC(Cl)=C2F)=O)=CN1)NC3=CC=C(CC4CCN(C)CC4)N=C3
Biological Activity: ERK5-IN-3 (compound 33j) is a potent and selective ERK5 (extracellular signal-related kinase 5) inhibitor, with an IC50 of 6 nM. ERK5-IN-3 shows antiproliferation activity against Hela cells, with an IC50 of 31 nM[1].
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ERK5-IN-3 | ERK5-IN-3 (compound 33j) is a potent and selective ERK5 (extracellular signal-related kinase 5) inhibitor, with an IC50 of 6 nM. ERK5-IN-3 shows antiproliferation activity against Hela cells, with an IC50 of 31 nM. | |||||||||||||||||||||
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References
Keywords
