18979-55-0
Chemical Structure
AC-45594
Synonym(s): 4-(Hexyloxy)phenol
- CAS No.: 18979-55-0
- Formula:C12H18O2
- Molecular Weight:194.27
IUPAC Name: 4-(hexyloxy)phenol
InChIKey: XIIIHRLCKLSYNH-UHFFFAOYSA-N
SMILES: CCCCCCOC1=CC=C(O)C=C1
Biological Activity: AC-45594 (4-(Hexyloxy)phenol) is a UPR activator. AC-45594 induces endoplasmic reticulum stress, activates the unfolded protein response (UPR), and drives the transition from adaptive stress signaling to terminal stress signaling, ultimately leading to cell Apoptosis. AC-45594 activates Caspase-3, induces PARP cleavage, and increases the protein level of DR5. AC-45594 selectively inhibits the growth of Ewing sarcoma cells[1].
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AC-45594 | 99.94% | AC-45594 (4-(Hexyloxy)phenol) is a UPR activator. AC-45594 induces endoplasmic reticulum stress, activates the unfolded protein response (UPR), and drives the transition from adaptive stress signaling to terminal stress signaling, ultimately leading to cell Apoptosis. AC-45594 activates Caspase-3, induces PARP cleavage, and increases the protein level of DR5. AC-45594 selectively inhibits the growth of Ewing sarcoma cells. | ||||||||||||||||||||
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Keywords