194737-13-8
Chemical Structure
Acetyljujuboside B
- CAS No.: 194737-13-8
- Formula:C54H86O22
- Molecular Weight:1087.25
InChIKey: JCNHTOHJIDUGID-MDSFCDLTSA-N
SMILES: C[C@]12[C@@]34[C@@](CC[C@]1([H])[C@@]5([C@@](C(C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@H](CO6)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)COC(C)=O)O)O)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)C)([H])CC2)C)([H])[C@]%10([H])[C@@](OC4)(O[C@H](C[C@@]%10(O)C)/C=C(C)\C)C3
Biological Activity: Acetyljujuboside B is a saponin. Acetyljujuboside B can be isolated from seeds of Zizyphus jujuba Mill. var. spinosa. Acetyljujuboside B inhibits Ca2+ influx. Acetyljujuboside B shows only sustained vasorelaxant effects, with no transient effect on NE-induced vasoconstrictions. Acetyljujuboside B inhibits histamine release from rat peritoneal exudate cells induced by the antigen-antibody reaction[1][2].
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Acetyljujuboside B | Acetyljujuboside B is a saponin. Acetyljujuboside B can be isolated from seeds of Zizyphus jujuba Mill. var. spinosa. Acetyljujuboside B inhibits Ca2+ influx. Acetyljujuboside B shows only sustained vasorelaxant effects, with no transient effect on NE-induced vasoconstrictions. Acetyljujuboside B inhibits histamine release from rat peritoneal exudate cells induced by the antigen-antibody reaction. | |||||||||||||||||||||
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References
- [1]. Iizuka T, et al. Saponins from seeds of Zizyphus jujuba Mill. var. spinosa exhibit vasorelaxant effects on rat isolated aorta. Traditional & Kampo Medicine, 2024, 11(2): 114-121.
- [2]. Hua Y, et al. Wild Jujube (Ziziphus jujuba var. spinosa): A Review of Its Phytonutrients, Health Benefits, Metabolism, and Applications. J Agric Food Chem. 2022 Jul 6;70(26):7871-7886. [Content Brief]
