220862-64-6
220862-64-6
Chemical Structure
LY433771
Synonym(s): LSN433771
- CAS No.: 220862-64-6
- Formula:C22H24N2O4
- Molecular Weight:380.44
InChIKey: XQHXEBCEJGFYFD-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC2=C1C3=C(N2CC4CCCCC4)C=CC=C3OCC(O)=O)N
Biological Activity: LY433771 (LSN433771) (Compound 8) is a type X secretory phospholipase A2 (sPLA2) inhibitor with an IC50 value of 3 nM, which can be used in the study of cardiovascular diseases[1][2].
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LY433771 | 99.8% | LY433771 (LSN433771) (Compound 8) is a type X secretory phospholipase A2 (sPLA2) inhibitor with an IC50 value of 3 nM, which can be used in the study of cardiovascular diseases. | ||||||||||||||||||||
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References
- [1]. Takashi Ono, et al. V TYPE AND/OR X TYPE sPLA2 INHIBITORS. Patent, WO2001026653, 2001-04-19.
- [2]. Magrioti V, Kokotos G. Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases[J]. Expert opinion on therapeutic patents, 2010, 20(1): 1-18. [Content Brief]
