2237953-19-2
2237953-19-2
Chemical Structure
PI3Kα-IN-5
- CAS No.: 2237953-19-2
- Formula:C30H35N9O5
- Molecular Weight:601.66
IUPAC Name: (S)-1-(4-(3-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)ureido)benzoyl)pyrrolidine-2-carboxamide
InChIKey: XDXZHIQVJAQRGY-DEOSSOPVSA-N
SMILES: O=C([C@H]1N(C(C2=CC=C(NC(NC3=CC=C(C4=NC(N5CCOCC5)=NC(N6CCOCC6)=N4)C=C3)=O)C=C2)=O)CCC1)N
Biological Activity: PI3Kα-IN-5 (compound 6 ab) is a potent PI3Kα/mTOR inhibitor, with an IC50 of 0.7 nM and 3.3 nM, respectively. PI3Kα-IN-5 can be used for the research of colorectal cancer[1].
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PI3Kα-IN-5 | PI3Kα-IN-5 (compound 6 ab) is a potent PI3Kα/mTOR inhibitor, with an IC50 of 0.7 nM and 3.3 nM, respectively. PI3Kα-IN-5 can be used for the research of colorectal cancer. | |||||||||||||||||||||
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References
Keywords
