23062-06-8
Chemical Structure
Fasedienol
Synonym(s): PH94B
- CAS No.: 23062-06-8
- Formula:C19H28O
- Molecular Weight:272.43
IUPAC Name: (3S,8S,9S,10R,13R,14S)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: NYVFCEPOUVGTNP-DYKIIFRCSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CCC1=C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(C=CC4)C
Biological Activity: Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety[1][2][3].
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Fasedienol | 99.68% | Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety. | ||||||||||||||||||||
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- [1]. Clive L. Jennings-White, et al. Steroids as neurochemical stimulators of the vno to alleviate symptoms of anxiety. Patent WO1998014194A1.
- [2]. Monti L, et al. Effect of fasedienol (PH94B) pherine nasal spray and steroidal hormones on electrogram responses and autonomic nervous system activity in healthy adult volunteers[J]. Human Psychopharmacology: Clinical and Experimental, 2024, 39(2): e2892. [Content Brief]
- [3]. Monti L, et al. Neural circuits of anxiolytic and antidepressant pherine molecules. CNS Spectr. 2022 Feb;27(1):66-72. [Content Brief]
Keywords
