2377301-45-4
2377301-45-4
Chemical Structure
Tubulin polymerization-IN-12
- CAS No.: 2377301-45-4
- Formula:C23H23N5O6
- Molecular Weight:465.46
IUPAC Name: 1-(5-methyl-7-(4-nitrophenyl)-2-(3,4,5-trimethoxyphenyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one
InChIKey: BIJAVPTZJZKFOX-UHFFFAOYSA-N
SMILES: COC1=CC(C2=NC3=NC(C)=C(C(N3N2)C4=CC=C(C=C4)[N+]([O-])=O)C(C)=O)=CC(OC)=C1OC
Biological Activity: Tubulin polymerization-IN-12 is a tubulin polymerization inhibitor (IC50=0.75 μM). Tubulin polymerization-IN-12 arrests cell cycle at G2/M phase, and exhibits cytotoxicity against cancer cells[1].
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Tubulin polymerization-IN-12 | Tubulin polymerization-IN-12 is a tubulin polymerization inhibitor (IC50=0.75 μM). Tubulin polymerization-IN-12 arrests cell cycle at G2/M phase, and exhibits cytotoxicity against cancer cells. | |||||||||||||||||||||
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