2415085-44-6
2415085-44-6
Chemical Structure
PF-07038124
- CAS No.: 2415085-44-6
- Formula:C18H22BNO4
- Molecular Weight:327.18
IUPAC Name: (R)-4-(5-(4-methoxy-3-propoxyphenyl)pyridin-3-yl)-1,2-oxaborolan-2-ol
InChIKey: KXVKOYCGACSUPP-INIZCTEOSA-N
SMILES: CCCOC1=C(OC)C=CC(C2=CN=CC([C@@]3([H])CB(OC3)O)=C2)=C1
Biological Activity: PF-07038124 is a PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. PF-07038124 shows inhibitory activities against IL-13, IL4, and IFNγ (IC50=125, 4.1, 1.06 nM, respectively). PF-07038124 can be used for research of atopic dermatitis and plaque psoriasis[1][2].
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PF-07038124 | PF-07038124 is a PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. PF-07038124 shows inhibitory activities against IL-13, IL4, and IFNγ (IC50=125, 4.1, 1.06 nM, respectively). PF-07038124 can be used for research of atopic dermatitis and plaque psoriasis. | |||||||||||||||||||||
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