2482998-39-8
2482998-39-8
Chemical Structure
HDAC1-IN-4
- CAS. Nr.: 2482998-39-8
- Formula:C21H24BrClN6O2
- Molecular Weight:507.81
IUPAC Name: 2-(2-((6-bromo-1-methyl-1H-indol-3-yl)methyl)-2,6-diazaspiro[3.4]octan-6-yl)-N-hydroxypyrimidine-5-carboxamide hydrochloride
InChIKey: QDAASXJSKUPZGE-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(N(CC2)CC32CN(CC4=CN(C)C5=C4C=CC(Br)=C5)C3)N=C1)NO.[H]Cl
Biological Activity: HDAC1-IN-4 (JX34) is a potent Plasmodium falciparum HDAC1 inhibitor shows antimalarial activity (IC50 < 5 nM) and lower cytotoxicity[1].
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HDAC1-IN-4 | HDAC1-IN-4 (JX34) is a potent Plasmodium falciparum HDAC1 inhibitor shows antimalarial activity (IC50 < 5 nM) and lower cytotoxicity. | |||||||||||||||||||||
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References
Keywords
