2495324-66-6
Chemical Structure
ALG-001075
- CAS No.: 2495324-66-6
- Formula:C22H19FN4O4
- Molecular Weight:422.41
InChIKey: CFNQUHVMFGMRDC-UHFFFAOYSA-N
SMILES: N#CC1=CC(NC(C2=C(C)C(C(C(NC3(COC3)C#C)=O)=O)=C(C)N2C)=O)=CC=C1F
Biological Activity: ALG-001075, a capsid assembly modulator (CAM), is an orally active HBV inhibitor. ALG-001075 effectively blocks not only HBV DNA production but also extracellular HBsAg/HBeAg and intracellular HBV RNA in primary human hepatocytes. ALG-001075 shows pronounced reductions of circulating HBV DNA in the AAV-HBV mouse model. ALG-001075 can be used for the study of Chronic hepatitis B (CHB)[1].
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ALG-001075 | 98.83% | ALG-001075, a capsid assembly modulator (CAM), is an orally active HBV inhibitor. ALG-001075 effectively blocks not only HBV DNA production but also extracellular HBsAg/HBeAg and intracellular HBV RNA in primary human hepatocytes. ALG-001075 shows pronounced reductions of circulating HBV DNA in the AAV-HBV mouse model. ALG-001075 can be used for the study of Chronic hepatitis B (CHB). | ||||||||||||||||||||
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Keywords