2757145-67-6
Chemical Structure
Antitumor agent-53
- CAS No.: 2757145-67-6
- Formula:C24H18FN3O
- Molecular Weight:383.42
IUPAC Name: 14-(3-fluorophenyl)-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
InChIKey: GAWLARQICSTTDL-UHFFFAOYSA-N
SMILES: O=C1C2=C(N(C3C4=C(C5=CC=CC=C5N4)CCN13)C6=CC=CC(F)=C6)C=CC=C2
Biological Activity: Antitumor agent-53 is a potent antitumor agent. Antitumor agent-53 induces cell cycle arrest at the G2/M phase. Antitumor agent-53 inhibits the PI3K/AKT pathway to induce the apoptosis of HGC-27 cells. Antitumor agent-53 has the potential for the research of gastrointestinal tumors[1].
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Antitumor agent-53 | Antitumor agent-53 is a potent antitumor agent. Antitumor agent-53 induces cell cycle arrest at the G2/M phase. Antitumor agent-53 inhibits the PI3K/AKT pathway to induce the apoptosis of HGC-27 cells. Antitumor agent-53 has the potential for the research of gastrointestinal tumors. | |||||||||||||||||||||
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Keywords