2849535-96-0
2849535-96-0
Chemical Structure
STAT3-IN-35
- CAS No.: 2849535-96-0
- Formula:C21H23NO4
- Molecular Weight:353.41
InChIKey: YKVUDUKZQAMEHP-ZDUSSCGKSA-N
SMILES: O=C(C1=O)C2=CC=CC=C2C3=C1C4=C(O3)CN(CC4)[C@H](CO)CC(C)C
Biological Activity: STAT3-IN-35 is a STAT3 inhibitor that binds to SH2 domain. STAT3-IN-35 inhibits the phosphorylation of STAT3 and possesses antiproliferative activities against triple-negative breast cancer (TNBC) cell lines. STAT3-IN-35 also has a toxicity and potent antitumor activity in a TNBC xenograft model[1].
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STAT3-IN-35 | STAT3-IN-35 is a STAT3 inhibitor that binds to SH2 domain. STAT3-IN-35 inhibits the phosphorylation of STAT3 and possesses antiproliferative activities against triple-negative breast cancer (TNBC) cell lines. STAT3-IN-35 also has a toxicity and potent antitumor activity in a TNBC xenograft model. | |||||||||||||||||||||
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