2924824-43-9

AKR1C3-IN-9 Chemical Structure
2924824-43-9

Chemical Structure

AKR1C3-IN-9

  • CAS No.: 2924824-43-9
  • Formula:C20H20N2O4
  • Molecular Weight:352.38

IUPAC Name: 2-oxo-2-(4-(pyridin-2-yl)piperazin-1-yl)ethyl 2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetate

InChIKey: JUPXIAWRJFYWOF-UHFFFAOYSA-N

SMILES: COC1=CC=CC=C1NC(C2=CC=CC=C2OCC3=C(ON=C3C)C)=O

Biological Activity: AKR1C3-IN-9 is a selective inhibitor of Aldo-keto Reductase 1C3 (AKR1C3) with an IC50 value of 8.92 nM. AKR1C3-IN-9 significantly reverses the Doxorubicin (HY-15142A) (DOX) resistance in a resistant breast cancer cell line[1].

Cat. No. Product Name Purity Description Pricing
HY-152188 		AKR1C3-IN-9 99.77% AKR1C3-IN-9 is a selective inhibitor of Aldo-keto Reductase 1C3 (AKR1C3) with an IC50 value of 8.92 nM. AKR1C3-IN-9 significantly reverses the Doxorubicin (HY-15142A) (DOX) resistance in a resistant breast cancer cell line.
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