3084159-97-4
3084159-97-4
Chemical Structure
SH-273
- CAS No.: 3084159-97-4
- Formula:C43H36N10O8S
- Molecular Weight:852.87
InChIKey: CDKHIFXQRBCTPX-QHCPKHFHSA-N
SMILES: O=C1C(C2=C3)=C(C(N1CCC(OCCN4C=C(C5=C6C(C=C(N(C7=CC=CC=C7)C6=O)[C@H](C)NC(C8=C9N(C=CC=N9)N=C8N)=O)=CC=C5)N=N4)=O)=O)SC2=CC(OC)=C3OC
Biological Activity: SH-273 is a dual targeting compound. SH-273 has dual function to stimulate STING function (EC50: 100 nM) and inhibits PI3Kγ (IC50: 7 nM). SH-273 can be used in the research of pancreatic cancer[1].
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SH-273 | SH-273 is a dual targeting compound. SH-273 has dual function to stimulate STING function (EC50: 100 nM) and inhibits PI3Kγ (IC50: 7 nM). SH-273 can be used in the research of pancreatic cancer. | |||||||||||||||||||||
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References
Keywords
