3094970-14-3
Chemical Structure
IMPDH-IN-1
- CAS No.: 3094970-14-3
- Formula:C19H18ClN5O3
- Molecular Weight:399.83
InChIKey: FCHBAAGOQDDDRN-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(Cl)C([N+]([O-])=O)=C1)NC(C)(C2=CC=CC(C3=CNC=N3)=C2)C
Biological Activity: IMPDH-IN-1 (compound 44) is a bacterial inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor. IMPDH-IN-1 specifically binds to the catalytic domain of IMPDH. IMPDH-IN-1 potently inhibits the IMPDH of Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli[1].
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IMPDH-IN-1 | IMPDH-IN-1 (compound 44) is a bacterial inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor. IMPDH-IN-1 specifically binds to the catalytic domain of IMPDH. IMPDH-IN-1 potently inhibits the IMPDH of Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. | |||||||||||||||||||||
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Keywords